Michael Holmes

• Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.

  Journal article

  Holmes MV. et al, (2017), Nat Rev Cardiol, 14, 577 - 590

• Genetic and epigenetic studies of adiposity and cardiometabolic disease.

  Journal article

  Holmes MV. et al, (2017), Genome Med, 9

• Education and coronary heart disease: mendelian randomisation study.

  Journal article

  Tillmann T. et al, (2017), BMJ, 358

• Association of Body Mass Index With Cardiometabolic Disease in the UK Biobank: A Mendelian Randomization Study.

  Journal article

  Lyall DM. et al, (2017), JAMA Cardiol, 2, 882 - 889

• Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

  Journal article

  Zewinger S. et al, (2017), Lancet Diabetes Endocrinol, 5, 534 - 543

• Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.

  Journal article

  Dale CE. et al, (2017), Circulation, 135, 2373 - 2388

• Mendelian randomisation in cardiovascular research: an introduction for clinicians.

  Journal article

  Bennett DA. and Holmes MV., (2017), Heart

• Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

  Journal article

  Zewinger S. et al, (2017), Lancet Diabetes and Endocrinology

• Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms.

  Journal article

  van 't Hof FN. et al, (2017), Eur J Hum Genet

• Cannabis use and risk of schizophrenia: a Mendelian randomization study.

  Journal article

  Vaucher J. et al, (2017), Mol Psychiatry

• Association between diabetes and cause-specific mortality in rural and urban China

  Journal article

  Bragg F. et al, (2017), JAMA

• Diabetes, plasma glucose and incidence of pancreatic cancer: A prospective study of 0.5 million Chinese adults and a meta-analysis of 22 cohort studies.

  Journal article

  Pang Y. et al, (2017), Int J Cancer

• Commentary: Mendelian randomization-inspired causal inference in the absence of genetic data.

  Journal article

  Zuccolo L. and Holmes MV., (2016), Int J Epidemiol

• A Loss-of-Function Variant in CETP Is Associated With Altered Lipid Metabolism but Not With Cardiovascular Disease Incidence in Chinese Adults

  Conference paper

  Chen Z. et al, (2016), CIRCULATION, 134, E711 - E711

• Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.

  Journal article

  Nüesch E. et al, (2016), Int J Epidemiol, 45, 1927 - 1937

• Body-mass index and cardiometabolic disease: a Mendelian randomisation study of UK Biobank participants

  Conference paper

  Lyall DM. et al, (2016), LANCET, 388, 9 - 9

• Long-Term Survival and Freedom From Reintervention After Off-Pump Coronary Artery Bypass Grafting: A Propensity-Matched Study.

  Journal article

  Kirmani BH. et al, (2016), Circulation, 134, 1209 - 1220

• Genetic analysis of emerging risk factors in coronary artery disease.

  Journal article

  van Iperen EP. et al, (2016), Atherosclerosis, 254, 35 - 41

• Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes.

  Journal article

  White J. et al, (2016), JAMA cardiology

• Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study.

  Journal article

  van der Laan SW. et al, (2016), Journal of the American College of Cardiology, 68, 934 - 945

• The relationship between body mass index and 10-year trajectories of physical functioning in middle-aged and older Russians: Prospective results of the Russian HAPIEE study

  Journal article

  Hu Y. et al, (2016), Journal of Nutrition, Health and Aging, 1 - 8

• Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

  Journal article

  Gan W. et al, (2016), Diabetologia, 59, 1446 - 1457

• Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.

  Journal article

  Swerdlow DI. et al, (2016), International Journal of Epidemiology

• Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk.

  Journal article

  Tragante V. et al, (2016), Hum Genet, 135, 453 - 467

• Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.

  Journal article

  White J. et al, (2016), The lancet. Diabetes & endocrinology, 4, 327 - 336

• Application of Advanced Mendelian Randomization Methods, to Investigate Whether Low Education Causes Coronary Heart Disease

  Conference paper

  Tillmann T. et al, (2016), HUMAN HEREDITY, 81, 230 - 231

• Deciphering the Causal Role of sPLA2s and Lp-PLA2 in Coronary Heart Disease.

  Journal article

  Talmud PJ. and Holmes MV., (2015), Arterioscler Thromb Vasc Biol, 35, 2281 - 2289

• Harnessing publicly available genetic data to prioritize therapeutic targets for cardiovascular prevention

  Conference paper

  Holmes MV. et al, (2015), EUROPEAN HEART JOURNAL, 36, 293 - 294

• A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.

  Journal article

  Sluijs I. et al, (2015), Diabetes, 64, 3028 - 3036

• Mendelian randomization of blood lipids for coronary heart disease.

  Journal article

  Holmes MV. et al, (2015), Eur Heart J, 36, 539 - 550

• Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

  Journal article

  Holmes MV. et al, (2014), BMJ, 349

• Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.

  Journal article

  Tragante V. et al, (2014), Am J Hum Genet, 94, 349 - 360

• Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.

  Journal article

  Holmes MV. et al, (2013), J Am Coll Cardiol, 62, 1966 - 1976

• Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

  Journal article

  Asselbergs FW. et al, (2012), Am J Hum Genet, 91, 823 - 838

• Blood Pressure Loci Identified with a Gene-Centric Array.

  Journal article

  Johnson T. et al, (2011), Am J Hum Genet, 89, 688 - 700

• Young adulthood and adulthood adiposity in relation to incidence of pancreatic cancer: a prospective study of 0.5 million Chinese adults and a meta-analysis

  Journal article

  Pang Y. et al, Journal of Epidemiology and Community Health

• CETP gene variants and risk of vascular and non-vascular diseases in ~150,000 Chinese adults

  Journal article

  Millwood IY. et al, JAMA Cardiology

• Validity of COPD diagnoses reported through nationwide health insurance systems in the People’s Republic of China

  Journal article

  Kurmi OP. et al, The International Journal of Chronic Obstructive Pulmonary Disease

• PCSK9 genetic variants and risk of type 2 diabetes: a Mendelian randomisation study

  Journal article

  Preiss D. et al, The Lancet Diabetes and Endocrinology

Recent Publications

• Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.

  Journal article

  Holmes MV. et al, (2017), Nat Rev Cardiol, 14, 577 - 590

• Genetic and epigenetic studies of adiposity and cardiometabolic disease.

  Journal article

  Holmes MV. et al, (2017), Genome Med, 9

• Education and coronary heart disease: mendelian randomisation study.

  Journal article

  Tillmann T. et al, (2017), BMJ, 358

• Association of Body Mass Index With Cardiometabolic Disease in the UK Biobank: A Mendelian Randomization Study.

  Journal article

  Lyall DM. et al, (2017), JAMA Cardiol, 2, 882 - 889

• Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

  Journal article

  Zewinger S. et al, (2017), Lancet Diabetes Endocrinol, 5, 534 - 543