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Balancing treatment allocations by clinician or center in randomized trials allows unacceptable levels of treatment prediction.
OBJECTIVE: Randomized controlled trials are the standard method for comparing treatments because they avoid the selection bias that might arise if clinicians ...
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An Overview of Methods and Exemplars of the Use of Mendelian Randomisation in Nutritional Research.
Objectives: It is crucial to elucidate the causal relevance of nutritional exposures (such as dietary patterns, food intake, macronutrients intake, circulating ...
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A practical method of measuring glomerular filtration rate by iohexol clearance using dried capillary blood spots.
BACKGROUND: Exogenous tracer-based methods of measuring glomerular filtration rate (GFR) are difficult to perform, whilst creatinine-based estimation formulae ...
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The number needed to treat (NNT) can be adjusted for bias when the outcome is measured with error.
BACKGROUND AND OBJECTIVE: We consider the number needed to treat (NNT) when the event of interest is defined by dichotomizing a continuous response at a ...
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Maternal and perinatal Health Research Collaboration, India (MaatHRI): methodology for establishing a hospital-based research platform in a low and middle income country setting.
Background: Maternal and perinatal Health Research collaboration, India (MaatHRI) is a research platform that aims to improve evidence-based pregnancy care and ...